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Guidance for Healthcare Professionals
The non-hormonal, FDA
cleared birth control app
Explore the software application for contraception that’s clinically proven & backed by science.
Clinical effectiveness
NC° Birth Control’s effectiveness and safety have been demonstrated across 10 peer-reviewed clinical studies, including one of the largest analyses of its kind. The real-life effectiveness of the method remains in line with published rates.
References: FDA De Novo DEN170052.
NC° Birth Control Pearl Index
7 out of 100 became pregnant within one year
5 from incorrect use (unprotected intercourse on fertile days)
2 despite perfect use, of which 0.5 result from the app incorrectly identifying a non-fertile day
Overview of NC° Birth Control
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How NC° Birth Control works
The AI-enhanced algorithm behind the app confirms each user’s daily fertility status by analyzing temperature data, menstrual data & optional LH tests. To prevent pregnancy, users agree to abstain or use protection on fertile days.
Overview of NC° Birth Control
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How biomarkers are collected
Wearables track temperature trends during sleep and automatically sync data to the NC° app.
The Natural Cycles app is compatible with multiple wearable technologies, including our NC° Band.
Patient eligibility
NC° Birth Control may be a good option for those seeking a non-hormonal, non-invasive method of contraception.
NC° Birth Control is suitable for those who:
Are 18 years or older- Agree to use protection or abstain on fertile days
- Cannot tolerate hormonal contraception
- Currently use a period tracker or less effective method
NC° Birth Control is certified for use as a contraceptive in the US, Canada, EU, UK, Australia, South Korea, Singapore and Brazil.
Comparison of contraceptive effectiveness data
NC° Birth Control is more effective than calendar-based FABMs and is in the same effectiveness category as the pill.
NC° Birth Control
98% Perfect use
IUD
Contraceptive pill
Natural Cycles°
Male condom
Pull out method
Calendar methodStarting impactful conversations
In 2025 Natural Cycles launched the UK Digital Contraception & Innovation Committee — the first of its kind.
The committee aims to:
Unite experts in contraception, women’s health & digital innovation
Develop tangible resources and educational materials on digital contraception
Advocate for better access to diverse contraceptive options in the UK
Meet the NC° Medical Advisory Board
Dr. Barbara Levy
MD, FACOG, FACS, MSCP
NC° Medical Advisory Board
”For far too long women have had few dependable, hormone-free birth control options, so I'm excited to partner with Natural Cycles to offer a valuable non-hormonal choice for those seeking it.”
Dr. Karen Tang
MD, MPH, FACOG
NC° Medical Advisory Board
”I was absolutely amazed at the amount of research and data that has gone into the creation of the NC° app. They're using cutting-edge technology and science to provide a birth control method that those seeking a hormone-free option deserve.”
Backed by research
Our dedicated on-staff Medical & Research Team has published over 20 peer-reviewed studies, advancing our mission to empower women and further the field of female health.
Access educational resources
Download printable resources developed by the Natural Cycles Medical & Science Team.
Prefer printed copies for your clinic?
Easily request free printed brochures, user manuals, and charts delivered to your clinic.
Contact Natural Cycles°
Contact us about potential partnerships or research collaborations, to request printed materials, get more information, or access a demo.
Dr. Kerry Krauss
OB-GYN & Senior Medical Advisor for Natural Cycles
Common questions
Natural Cycles uses a subscription model, available as an annual or monthly plan. Users can purchase their subscription through our website, their app store, and in some pharmacies. All subscriptions includes access to all modes including NC° Birth Control, NC° Plan Pregnancy, NC° Follow Pregnancy and NC° Postpartum.
Please be aware that when prescribing NC° Birth Control, the Annual Plan is the only option that is currently available for insurance reimbursement.
NC° Birth Control is a non-hormonal, non-invasive contraceptive method that’s FDA Cleared. It may be a option for those who:
- Are 18 years or older
- Agree to use protection or abstain on fertile days
- Cannot tolerate hormonal contraception
- Currently use a period tracker or less effective method
- Are looking to prevent pregnancy now, with a view to plan pregnancy in the future
NC° Birth Control is just as effective for users with irregular cycles, but they may be assigned more fertile days, which may reduce satisfaction. Note that patients cannot use NC° Birth Control at the same time as hormonal contraception.
NC° Birth Control is the first and only contraceptive app to be FDA Cleared and CE marked. As such, the Natural Cycles app is a regulated medical device.
The AI-enhanced algorithm uses body temperature and other fertility indicators to confirm each user’s daily fertility status. Peer-reviewed research found that the algorithm finds fertile days more accurately than calendar-based methods (specifically, the Rhythm Method and Standard Days Method), and that it is less likely to incorrectly assign a non-fertile day. Read more about this research here.
Data security is a top priority for Natural Cycles and NC° Birth Control is designed to protect user data. Natural Cycles Data Protection Officer and Team use advanced security protocols, including pseudonymization and encryption, as part of our comprehensive privacy program.
Users who need an extra layer of identity protection have the option to Go Anonymous. In this optional mode, personal identifying information is separated from fertility data. That means that no one — not even Natural Cycles — can link a user to their data.
Because Natural Cycles charges a subscription fee, it doesn’t need to earn money by selling users’ data like some “free” apps. As a regulated medical device, Natural Cycles is required to comply with the FDA’s cybersecurity requirements. And as a Swedish company, the Natural Cycles app is designed to comply with European GDPR.